Immense ingenuity and unprecedented levels of funding are available in the drug discovery ecosystem, yet pharmaceutical research and development (R&D) is failing to produce the medicines that can tackle the challenging diseases of today and tomorrow, many with devastating consequences for our society. New organisational models of drug discovery are clearly needed, and this policy paper argues that open science approaches represent the most promising path forward by addressing both scientific and organisational bottlenecks. It reviews open science based initiatives at the University of Oxford and beyond, and examines their potential to increase the productivity of pharmaceutical R&D. The paper concludes by presenting a series of recommendations that would nurture and grow the open science component of the drug discovery ecosystem, potentially transforming how the medical challenges of this century are tackled in a way that is beneficial to patients and producers alike.
Other Recent Policy Papers
Can natural climate solutions resolve key trade-offs within the sustainable development goals?
The Economics of Mobile Money: harnessing the transformative power of technology to benefit the global poor.
All Change! The Implications of Non-stationarity for Empirical Modelling, Forecasting and Policy
Women's Health: a new global agenda
Short-Lived Promise? The Science and Policy of Cumulative and Short-Lived Climate Pollutants
Robo-Wars: The Regulation of Robotic Weapons