Nature Medicine
Nature Medicine 22, 606–613 (2016) doi:10.1038/nm.4100 Published online 16 May 2016
View Journal Article / Working PaperHuman immunodeficiency virus is known to be a highly variable virus that adapts to a person's immune response during the lifetime infection. This study shows that viral adaptation in HIV can predict a person's current disease status, as well as the degree to which newly transmitted HIV-1 is adapted to their new host.