Persistent HIV-1 replication maintains the tissue reservoir during therapy

26 January 2016

View Journal Article / Working Paper

A team of international researchers, including a mathematical modeller from the Oxford Martin School’s Programme on Infectious Diseases, has found that HIV is still replicating in the lymphoid tissue, even when it is undetectable in the blood of patients on antiretroviral drugs.

The study, led by Northwestern University, USA, is published in the journal Nature and its findings provide a critical new perspective on how HIV persists in the body despite potent antiretroviral therapy.