The number of people being diagnosed with heart failure in the UK continues to grow, and the poorest people are significantly more likely to be affected by the condition, new research from The George Institute for Global Health at the University of Oxford has found.

The study, published in The Lancet, shows that people in the most deprived socio-economic groups about 60% more likely to be affected by heart failure, furthermore, the gap between the richest and the poorest did not actually close at all between 2002 and 2014.

People in the poorest neighbourhoods are likely to be affected by heart failure about 3.5 years earlier in life than those in the wealthiest areas (at an average age of 74.5, compared with 78). Disparities between different socio-economic groups actually grew during the study period, with the age at which heart failure is diagnosed rising for the most affluent, but dropping slightly among the most deprived.

The research led by Professor Kazem Rahimi, Director of the Oxford Martin Programme on Deep Medicine, and Nathalie Conrad, analysed data on four million people to investigate trends and patterns in heart failure incidence across the UK.

Significant regional variations were found, with the highest incidence rates for heart failure in 2014 seen in the East Midlands (410-449 cases per 100,000 people); the North-West (370-409 cases per 100,000 people); and the North-East, Yorkshire and the Humber, and the West Midlands (all with 330-369 cases per 100,000 people). The lowest incidence rates were seen in the South East Coast region (250-289 cases per 100,000 people).

“These regional and socio-economic disparities in the incidence of heart failure and age at onset within the same country highlight the preventable nature of the disease, and suggest we still have a lot of work to do to tackle it,” said Conrad.

“If we could achieve the incidence rates we see among the most affluent groups for the population as a whole, we would observe a fall of about one-fifth or nearly 32,000 fewer cases every year.”

Further research is needed to understand what is behind the varying rates of heart failure in different communities. The discrepancies may be linked to the presence of other illnesses; to risk factors such as blood pressure, smoking and diet; or to a less effective use of drugs that can help prevent heart failure.

The study showed that heart failure affected nearly a million people in the UK in 2014; a rise of 23% from 2002. Despite modest improvements in prevention and an increase in the age at which patients develop the disease, there are now as many new cases of heart failure each year as there are of the four most common cancers combined (lung, breast, bowel and prostate).

An increase of ageing population in the UK largely explains the rise in incidences of heart failure. The number of people aged 65-69 rose by 36% between 2002 and 2014 and the post-war ‘baby boomer’ generation are now reaching an age at which they are at greater risk of heart failure.

The proportion of patients suffering three or more additional conditions was also seen to rise from 68% to 87% during the study period, showing a substantial increase in the number of other illnesses experienced by those with heart failure.

Professor Rahimi notes “the number of diseases associated with heart failure was high, and increased over time. This suggests that as the number of patients with heart failure grows, caring for them is also becoming more complex, increasing the burden on health services.”